1、A nice example of high grade dysplasia in Barrett’s esophagus.  This pattern has been termed ‘gastric‘ and ‘non-adenomatous’ to underscore the lack of elongated stratified nuclei. 一个巴雷特食管高级别异型增生的良好示例。这种模式被称为’胃型’和’非腺瘤性’,以强调缺乏拉长的分层细胞核。
2、This unusual gastric antral polyp is a pyloric gland adenoma with high grade dysplasia.  This type is often detected in the setting of autoimmune gastritis, arising in the gastric body in zones of pyloric metaplasia. 
这种不寻常的胃窦息肉是一种高分化主细胞腺瘤。这种类型通常在自身免疫性胃炎的背景下被检测到,起源于胃体部幽门化生区域。 
3、High grade dysplasia in gastric hyperplastic polyps.  This patient had H. pylori gastritis and many large gastric hyperplastic polyps, some with high-grade dysplasia.  Note the abrupt demarcation between dysplastic epithelium and  the  adjoining mucosa. http://

胃增生性息肉中的高级别异型增生。该患者患有幽门螺杆菌性胃炎,并且有很多大型胃增生性息肉,其中一些伴有高级别异型增生。注意异型增生上皮与相邻黏膜之间的突然界限。

4、This is a nice example of a gastric pyloric gland adenoma with high grade dysplasia. The patient had autoimmune gastritis.
这些胃黏膜病变,你会诊断高级别吗?
这是一个胃泌酸腺瘤伴有高度异型的良好实例。患者患有自身免疫性胃炎。

5、This Barrett’s esophagus has an unusual pattern of high grade dysplasia – the differentiation is not classically intestinal.  It is more reminiscent of that seen in a pyloric gland adenoma.  The background nondysplastic mucosa had typical incomplete intestinal metaplasia.
这种巴雷特食管具有一种不寻常的高级别异型增生模式——分化并非典型肠化生。它更像是幽门腺腺瘤中看到的病变。背景的非异型增生黏膜具有典型的不完全肠化生。

6、幽门腺瘤伴高级别异型增生。
7、This gastric pyloric gland adenoma features not only squamous morules (arrows) but also has highgradedysplasia.  This type is associated with autoimmune gastritis/pernicious anemia and is covered in the forthcoming AFIP Esophagus and Stomach Fascicle.  
这种胃底腺腺瘤不仅具有鳞状小体(箭头所示),还存在高级别异型增生。这种类型与自身免疫性胃炎/恶性贫血相关,将在即将出版的 AFIP 食管和胃专集中进行介绍。 
8,85随胃息肉,高级别异型增生。
9、P53缺失模式高级别异型增生

10、增生性息肉伴高级别异型增生。